"It makes no difference night or day, the shadow never seems to fade away"

This lyric is amazingly sorrowful lyric for anyone whose experienced a break up or the loss of someone close. From a Canadian country, folk, rhythm and blues band simply called "The Band". The songs depicts a sad shame filled person whose lost the one they love and it makes no differences what happens in their life, the pain still feels the same. So when the man says "It makes no difference, night or day, the shadow never seems to fade away" He's says that no matter what happens, it can be night or day, rain or shine, cold or warm, the shadow, Which is a metaphor for the pain he feels never can go away. His pain and anguish will remain.
To me the line has deep feeling, coming from the heart of someone who has felt this pain before, much like we all have. I've experienced a few running their course break up's and I've too felt the feelings this person has felt when they've lost the one thing that makes there night and day. The person who is their shadow, the person that is there life, and no matter what happens, we all can't seem to make that feeling of stone cold heart break go away.